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The 10 Worst Medications for Your Kidneys

When it comes to medications, some can put a strain on your kidneys. Here are ten that are generally considered to have a higher risk of kidney damage:

  1. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): These include ibuprofen (Advil, Motrin) and naproxen (Aleve). They can reduce blood flow to the kidneys, leading to kidney damage or failure if used excessively or for prolonged periods.
  2. Acetaminophen (Tylenol): While not as directly harmful to the kidneys as NSAIDs, high doses or long-term use can cause kidney damage.
  3. Proton Pump Inhibitors (PPIs): Drugs like omeprazole (Prilosec), esomeprazole (Nexium), and lansoprazole (Prevacid) used to treat acid reflux and ulcers have been associated with an increased risk of kidney damage.
  4. Certain Antibiotics: Antibiotics like vancomycin, gentamicin, and ciprofloxacin can be nephrotoxic, meaning they can directly damage the kidneys.
  5. Certain Antiviral Medications: Some antiviral drugs used to treat HIV, such as tenofovir (Viread), can cause kidney damage.
  6. Certain Antifungal Medications: Drugs like amphotericin B, used to treat serious fungal infections, can be nephrotoxic.
  7. Certain Blood Pressure Medications: Some blood pressure medications, particularly angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs), can cause kidney damage in certain individuals.
  8. Diabetes Medications: Certain diabetes medications, such as metformin (particularly in those with pre-existing kidney issues) and certain types of insulin, can affect kidney function.
  9. Lithium: This medication is used to treat bipolar disorder but can cause kidney damage, particularly when used long-term.
  10. Cyclosporine: This immunosuppressant drug, used to prevent rejection in organ transplant recipients, can cause kidney damage over time.

It’s important to note that while these medications can potentially harm the kidneys, they are also often necessary for treating various medical conditions. Always consult with a healthcare professional before starting or stopping any medication, and be sure to discuss any concerns about kidney health. Additionally, regular monitoring of kidney function is important for individuals taking these medications.